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MENG Hei, XU Yong. Preparation of Polyelectrolyte microcapsules of TiO2 sunscreen cream[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 38-41. doi: 10.3969/j.issn.1006-0111.2012.01.010
Citation: MENG Hei, XU Yong. Preparation of Polyelectrolyte microcapsules of TiO2 sunscreen cream[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 38-41. doi: 10.3969/j.issn.1006-0111.2012.01.010

Preparation of Polyelectrolyte microcapsules of TiO2 sunscreen cream

doi: 10.3969/j.issn.1006-0111.2012.01.010
  • Received Date: 2011-08-22
  • Rev Recd Date: 2011-11-01
  • Objective To investigate the preparation method, the structure and the sun protection factor (SPF) of the polyelectrolyte self-assembled microcapsules containing TiO2 nanoparticles. Methods Calcium carbonate was used as the core, and the semipermeable membrane outside the core was made of poly (sodium 4-styrenesulfonate) (PSS) and TiO2 depositing onto the core surface alternately through electrostatic attraction. The morphology and the structure of the microcapsules were obtained by confocal laser scanning microscopy and scanning electron microscopy. The SPF was tested by SPF-290 analytical system. Results The prepared microcapsules were well-shaped with a mean diameter of (5.46±1.05) μm. The SPF was 30.31±2.56. Conclusion It was indicated that in comparison with traditional TiO2 sunscreen cream, the polyelectrolyte microcapsules containing titania had powerful absorbance of the ultraviolet rays.
  • [1] Touitou E, Godin B. Skin nonpenetrating sunscreens for cosmetic and pharmaceutical formulations[J].Clin Dermatol, 2008, 26(4):375.
    [2] Sadrieh N, Wokovich AM, Gopee NV, et al. Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano-and submicron-size TiO2 particles[J].Toxicol Sci, 2010, 115(1):156.
    [3] Ai H. Layer-by-layer capsules for magnetic resonance imaging and drug delivery[J].Adv Drug Deliv Rev, 2011, 63(9):772.
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    [5] Boudou T, Crouzier T, Ren K, et al. Multiple functionalities of polyelectrolyte multilayer films: new biomedical applications[J].Adv Mater, 2010, 22(4):441.
    [6] 张晟卯, 张治军, 党鸿辛,等.磺化聚苯乙烯/二氧化钛有序交替纳米复合多层膜的制备、结构表征及其微观摩擦学行为[J].河南大学学报, 2003, 3(1):38.
    [7] Sukhorukov GB, Volodkin DV, Gunther AM, et al. Porouscalcium carbonate microparticles as templates for encapsulation of bioactive compounds[J].J Mater Chem, 2004, 14(14): 2073.
    [8] Wang CY, He CY , Tong Z, et al.Combination of adsorption by porous CaCO3 microparticles and encapsulation by polyelectrolyte multilayer films for sustained drug delivery[J].Int J Pharm, 2006, 308(1-2):160.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Preparation of Polyelectrolyte microcapsules of TiO2 sunscreen cream

doi: 10.3969/j.issn.1006-0111.2012.01.010

Abstract: Objective To investigate the preparation method, the structure and the sun protection factor (SPF) of the polyelectrolyte self-assembled microcapsules containing TiO2 nanoparticles. Methods Calcium carbonate was used as the core, and the semipermeable membrane outside the core was made of poly (sodium 4-styrenesulfonate) (PSS) and TiO2 depositing onto the core surface alternately through electrostatic attraction. The morphology and the structure of the microcapsules were obtained by confocal laser scanning microscopy and scanning electron microscopy. The SPF was tested by SPF-290 analytical system. Results The prepared microcapsules were well-shaped with a mean diameter of (5.46±1.05) μm. The SPF was 30.31±2.56. Conclusion It was indicated that in comparison with traditional TiO2 sunscreen cream, the polyelectrolyte microcapsules containing titania had powerful absorbance of the ultraviolet rays.

MENG Hei, XU Yong. Preparation of Polyelectrolyte microcapsules of TiO2 sunscreen cream[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 38-41. doi: 10.3969/j.issn.1006-0111.2012.01.010
Citation: MENG Hei, XU Yong. Preparation of Polyelectrolyte microcapsules of TiO2 sunscreen cream[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 38-41. doi: 10.3969/j.issn.1006-0111.2012.01.010
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