Preparation of Puerarin by microemulsion drug delivery system

Chen Han; Zhong Yan-qiang; Lu Ying

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Volume 26 Issue 3

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Article Navigation > Journal of Pharmaceutical Practice and Service > 2008 > (3): 200-203

Chen Han, Zhong Yan-qiang, Lu Ying. Preparation of Puerarin by microemulsion drug delivery system[J]. Journal of Pharmaceutical Practice and Service, 2008, (3): 200-203.

Citation:

Chen Han, Zhong Yan-qiang, Lu Ying. Preparation of Puerarin by microemulsion drug delivery system[J]. Journal of Pharmaceutical Practice and Service, 2008, (3): 200-203.

Preparation of Puerarin by microemulsion drug delivery system

1.
China
2.
College of Pharmacy,Second Military Medical University,Shanghai 200433,China

Received Date: 2008-03-24

Abstract

Objective: To develop a microemulsion drug delivery system of Puerarin(PUE-ME). Methods: Formulation of PUE-ME was screened by solubility experiments,compatibility tests and pseudo-ternary phase diagrams,with the consequence of visual examination as parameter. Results: The maximum drug corporation was 77.11 mg/mL.The formulation was composed of IPM(10%),brij-96V(37.5%),ethanol(37.5%),and water(25%). Conclusion: The formulation of PUE-ME preparation could meet the general requirements of the design.
- puerarin,
- microemulsion,
- solubilization
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通讯作者: 陈斌, [email protected]

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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