Preparation and quality control of the aciclovir eye ointment

CAO Hui-ling; WANG Yang-zheng; ZHOU Guang-ying

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Volume 22 Issue 6

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Article Navigation > Journal of Pharmaceutical Practice and Service > 2004 > (6): 350-352

CAO Hui-ling, WANG Yang-zheng, ZHOU Guang-ying. Preparation and quality control of the aciclovir eye ointment[J]. Journal of Pharmaceutical Practice and Service, 2004, (6): 350-352.

Citation:

CAO Hui-ling, WANG Yang-zheng, ZHOU Guang-ying. Preparation and quality control of the aciclovir eye ointment[J]. Journal of Pharmaceutical Practice and Service, 2004, (6): 350-352.

Preparation and quality control of the aciclovir eye ointment

Institute of Xi'an ophthalmology, Xi'an 710002, China

Received Date: 2004-02-19

Abstract

Objective To prepare aciclovir eye ointment and establish a quality control standard. Methods The eye ointment was prepared with yellow vaseline, wool fat and anhydrous.RP-HPLC was applied to quantitative analysis. Results The average recovery rate of aciclovir was 98.47%,RSD was 1.20%(n=5).Conclusion The preparation of aciclovir eye ointment was simple, its property was stable and its quality can be controlled for the clinical use.The determination of content was accurate and rapid by RP-HPLC.
- aciclovir,
- eye ointment,
- RP-HPLC
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通讯作者: 陈斌, [email protected]

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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