Optimization of assay method for loganin in Gandi capsules

WEI Xin; XU Renjie; TANG Ying; YAO Huan; XU Ajing; ZHANG Jian

doi:10.3969/j.issn.1006-0111.2018.06.016

Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review, editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code

x Close Forever Close

PDF
Cite
Share

facebook

twitter

google

linkedin

Volume 36 Issue 6

Turn off MathJax

Article Contents

Article Navigation > Journal of Pharmaceutical Practice and Service > 2018 > 36(6): 551-553

WEI Xin, XU Renjie, TANG Ying, YAO Huan, XU Ajing, ZHANG Jian. Optimization of assay method for loganin in Gandi capsules[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(6): 551-553. doi: 10.3969/j.issn.1006-0111.2018.06.016

Citation:

WEI Xin, XU Renjie, TANG Ying, YAO Huan, XU Ajing, ZHANG Jian. Optimization of assay method for loganin in Gandi capsules[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(6): 551-553. doi: 10.3969/j.issn.1006-0111.2018.06.016

Optimization of assay method for loganin in Gandi capsules

doi: 10.3969/j.issn.1006-0111.2018.06.016

1.
Department of Pharmacy, Xinhua Hospital Affiliated to School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China
2.
Shanghai Fangxin Pharmaceutical Co., Ltd., Shanghai 200120, China

Received Date: 2018-06-01
Rev Recd Date: 2018-09-10

Abstract

Objective To establish a HPLC method for the assay of loganin in Gandi capsules. Methods The Waters Symmtry column C₁₈ (4.6 mm×150 mm, 5 μm) was used with acetonitrile-water (13:87) as mobile phase. The flow rate was 1.0 ml/min and the detection wavelength at 240 nm. Results The calibration curves were linear within the range of 0.030 1-3.01 μg (r=0.999 9) for loganin. The average recovery and relative standard deviation of loganin were 99.62% and 0.86%. Conclusion This method is simple, practicable, accurate and fast. It can be used to assay loganin in Gandi capsules.
- Gandi capsule,
- loganin,
- assay,
- HPLC

References

[1]	朱伟嵘,杨永华,郑岚,等. 甘地胶囊对糖尿病血瘀证治疗作用的临床观察[J]. 中华现代中西医杂志,2005,3(13):1153-1156
[2]	晁愚, 张昕. 甘地胶囊质量标准研究[J]. 中成药, 2007, 29(3):469-470.
[3]	曹含弘. 前列地尔联合甘地胶囊治疗早期糖尿病肾病疗效观察[J]. 山东医药, 2013, 53(24):80-81.
[4]	魏昕, 姚慧娟, 刘艳, 等. 甘地胶囊辅助治疗糖尿病肾病的疗效观察[J]. 中国药房, 2016, 27(2):225-227.
[5]	唐跃年, 凌启迪, 肖敏, 等. 甘地胶囊指纹图谱分析及指标成分含量测定[J].中国临床药学杂志, 2013, 22(5):299-303.
[6]	李逸飞, 马婉婷. 甘地胶囊指纹图谱分析及指标成分含量测定[J]. 内蒙古中医药, 2016, 35(17):147-148.

Proportional views

通讯作者: 陈斌, [email protected]

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Get Citation

PDF

XML

Article Metrics

Article views(3342) PDF downloads(371) Cited by()

Proportional views