Brief analysis the application of several signal monitoring methods in adverse drug events

DAI Fei; SHU Li-xin; CHU Cang; CHENG Sheng-xin; CHU Wen-gong

doi:10.3969/j.issn.1006-0111.2012.05.018

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Objective To analyze several adverse drug reaction monitoring methods in home and aboard. Methods Literature analysis and system analysis method were used to illustrate a series of calculation methods in signal extraction of adverse drug reaction. Results China had gradually begun to use different signal monitoring algorithms to detect adverse drug reaction (ADR) signals. Conclusion Medication safety issue still needed to be paid close attention to in current and future, and drug safety monitoring was mainly through the post-marketing adverse signal monitoring to achieve. Different data mining algorithms for relevant signal monitoring at home and in abroad were summarized, which would provide reference for our adverse drug reaction signal processing, and do good to the drug safety alert.

Brief analysis the application of several signal monitoring methods in adverse drug events

Department of Pharmacy Administration, Second Military Medical University, Shanghai 200433, China

Received Date: 2011-11-24

Rev Recd Date: 2012-05-16

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Abstract: Objective To analyze several adverse drug reaction monitoring methods in home and aboard. Methods Literature analysis and system analysis method were used to illustrate a series of calculation methods in signal extraction of adverse drug reaction. Results China had gradually begun to use different signal monitoring algorithms to detect adverse drug reaction (ADR) signals. Conclusion Medication safety issue still needed to be paid close attention to in current and future, and drug safety monitoring was mainly through the post-marketing adverse signal monitoring to achieve. Different data mining algorithms for relevant signal monitoring at home and in abroad were summarized, which would provide reference for our adverse drug reaction signal processing, and do good to the drug safety alert.

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Reference (13)

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Brief analysis the application of several signal monitoring methods in adverse drug events

doi: 10.3969/j.issn.1006-0111.2012.05.018

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通讯作者: 陈斌, [email protected]

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