2000 Vol. 18, No. 3
Display Method:
2000, (3): 131-133.
Abstract:
OBJECTIVE To study the effect of mannitol as pain-reliever for malignant tumor pain.METHODS 320 patients with malignant tumor pain,divided into once daily group and twice daily group,were given 20% mannitol 250ml by intravenous infusion.To compare the effect of relieve pain of mannitol,the malignant tumor patients treated with radiotherapy were divided into purely radiotherapy group and radiotherapy plus intravenous drip mannitol group.RESULTS The rates completely relieve about the two groups were 68.5% and 70.6%(P>0.05).The rates of 4,5 and 6 pain degree about purely radiotherapy were higher than that of radiotherapy plus mannitol group(12.5% and 0)(P<0.01).CONCLUSION Intravenous drip mannitol can prevent and kill the acute cancer pain and the pain results from radiotherapy.
OBJECTIVE To study the effect of mannitol as pain-reliever for malignant tumor pain.METHODS 320 patients with malignant tumor pain,divided into once daily group and twice daily group,were given 20% mannitol 250ml by intravenous infusion.To compare the effect of relieve pain of mannitol,the malignant tumor patients treated with radiotherapy were divided into purely radiotherapy group and radiotherapy plus intravenous drip mannitol group.RESULTS The rates completely relieve about the two groups were 68.5% and 70.6%(P>0.05).The rates of 4,5 and 6 pain degree about purely radiotherapy were higher than that of radiotherapy plus mannitol group(12.5% and 0)(P<0.01).CONCLUSION Intravenous drip mannitol can prevent and kill the acute cancer pain and the pain results from radiotherapy.
2000, (3): 134-136.
Abstract:
OBJECTIVE To investigate the efficacy and safety of topical intrathyroid injection of dexamethasone in the patients with subacute thyroiditis.METHODS Twenty patients with subacute thyroiditis were divided randomly into two groups.10 Patients (group A) were treated with topical intrathyroid injection of dexamethasone(5mg/ml,twice perweek),10 Patients (group B)were treated with prednisone 30 mg/d orally.Clinical outcomes of two groups are compared after 2 weeks,4 weeks and 8 weeks.RESULTS Curative rate of group A and group B after 8 weeks were 90% and 100% respectively and there were no significant difference(P>0.25).Duration of therapy were(5.6±2.1) weeks in group A and (8.2±1.8) weeks in group B respectively and there were significant difference (P<0.05).No adverse reactions occurred in both groups.CONCLUSIONS:Topical injection of dexamethasone in patients with subacute thyroiditis improves the symptoms rapidly and shorten the course of disease,so it is highly effective and safe.
OBJECTIVE To investigate the efficacy and safety of topical intrathyroid injection of dexamethasone in the patients with subacute thyroiditis.METHODS Twenty patients with subacute thyroiditis were divided randomly into two groups.10 Patients (group A) were treated with topical intrathyroid injection of dexamethasone(5mg/ml,twice perweek),10 Patients (group B)were treated with prednisone 30 mg/d orally.Clinical outcomes of two groups are compared after 2 weeks,4 weeks and 8 weeks.RESULTS Curative rate of group A and group B after 8 weeks were 90% and 100% respectively and there were no significant difference(P>0.25).Duration of therapy were(5.6±2.1) weeks in group A and (8.2±1.8) weeks in group B respectively and there were significant difference (P<0.05).No adverse reactions occurred in both groups.CONCLUSIONS:Topical injection of dexamethasone in patients with subacute thyroiditis improves the symptoms rapidly and shorten the course of disease,so it is highly effective and safe.
2000, (3): 147-149.
Abstract:
OBJECTIVE To measure the safety of Shenfuling(made from tretinoin、dimercaprol and salicylic acid)ointment.METHODS Acute toxicity tests and stimulation tests for skin and mucosa were used. RESULTS Shenfuling ointment had no toxicity and hypersentivity of skin and lower stimulation for skin and eyes.CONCLUION Shenfuling ointment has no toxicity.It can be used in the paitient of chronic arsenic poisoning.
OBJECTIVE To measure the safety of Shenfuling(made from tretinoin、dimercaprol and salicylic acid)ointment.METHODS Acute toxicity tests and stimulation tests for skin and mucosa were used. RESULTS Shenfuling ointment had no toxicity and hypersentivity of skin and lower stimulation for skin and eyes.CONCLUION Shenfuling ointment has no toxicity.It can be used in the paitient of chronic arsenic poisoning.
2000, (3): 149-150.
Abstract:
OBJECTIVE To obtain the optimum prescription of acelylspiramycin tablets.METHODS The effect of CMS-Na,L-HPC,and Tween-80 on the quality of acetylspiramycin tablets were studied.Its dissolvability was determined and compared with those manufactured by two different factories.RESULTS The results showed that acetylspiramycin tablets prepared with this optimum prescription was much better in terms of dissolvability.CONCLUSION The method is reasonable,simple,and prodruction suitable to pharmaceutical factiories.
OBJECTIVE To obtain the optimum prescription of acelylspiramycin tablets.METHODS The effect of CMS-Na,L-HPC,and Tween-80 on the quality of acetylspiramycin tablets were studied.Its dissolvability was determined and compared with those manufactured by two different factories.RESULTS The results showed that acetylspiramycin tablets prepared with this optimum prescription was much better in terms of dissolvability.CONCLUSION The method is reasonable,simple,and prodruction suitable to pharmaceutical factiories.
2000, (3): 151-153.
Abstract:
OBJECTIVE To introduce a new solid dosage form,a rapidly disintegrating tablet,which can be rapidly disintegrated and dissolved in the mouth within 15 second without drinking.METHODS Reviewed the relative articals in these years.RESULTS Among the articals,Low substituted hydroxypropylcellulose,microcrystalline cellulose and crosslinked sodium carboxymethyl cellulose or treated agar were used as disintegrants.Erythritol was selected to enhance palatability of the tablet.CONCLUSION It is necessary and practical to develop rapidly disintegrating tablet.
OBJECTIVE To introduce a new solid dosage form,a rapidly disintegrating tablet,which can be rapidly disintegrated and dissolved in the mouth within 15 second without drinking.METHODS Reviewed the relative articals in these years.RESULTS Among the articals,Low substituted hydroxypropylcellulose,microcrystalline cellulose and crosslinked sodium carboxymethyl cellulose or treated agar were used as disintegrants.Erythritol was selected to enhance palatability of the tablet.CONCLUSION It is necessary and practical to develop rapidly disintegrating tablet.
2000, (3): 154-156.
Abstract:
OBJECTIVE To provide a useful way of quality control,a first order derivative spectrophotometric method had been developed to determine the content and uniformity of content of fenfuramine hydrochloride tables.METHODS Water was selected for solvent.The first derivative spectrum was obtained by scanning from 280 to 220nm.The distance D of the derivative peak at 265nm and valley at 295nm was used as quantitative basis.The assay was calculated by comparing the peak-valley distance of sample with standard.RESULTS There was a good linear relationship between fenfuramine hydrochloride concentration in the range of 0.05～0.40mg/ml and the peak-valley distance of derivative spectrum with r=0.9999.The average recovery form sample was 100.6%. RSD=0.7%(n=6).CONCLUSIONS The proposed method is simple,accurate and reproducible.
OBJECTIVE To provide a useful way of quality control,a first order derivative spectrophotometric method had been developed to determine the content and uniformity of content of fenfuramine hydrochloride tables.METHODS Water was selected for solvent.The first derivative spectrum was obtained by scanning from 280 to 220nm.The distance D of the derivative peak at 265nm and valley at 295nm was used as quantitative basis.The assay was calculated by comparing the peak-valley distance of sample with standard.RESULTS There was a good linear relationship between fenfuramine hydrochloride concentration in the range of 0.05～0.40mg/ml and the peak-valley distance of derivative spectrum with r=0.9999.The average recovery form sample was 100.6%. RSD=0.7%(n=6).CONCLUSIONS The proposed method is simple,accurate and reproducible.
2000, (3): 157-158.
Abstract:
OBJECTIVE To establish a mothod for the determination of oleanolic acid in the fruit and leaves of Ligustrum obtusifolium Sieb.et Zucc.METHOD:Thin-layer scanning chromatography(TLC) was used.RESULTS The concentration of oleanolic acid was 0.395% in the fruit and 0.228% in the leaves.The average recovery rate was 99.3% and RSD was 2.08%.CONCLUSION The method is simple and reliable.The results are steady and reappearance is good.
OBJECTIVE To establish a mothod for the determination of oleanolic acid in the fruit and leaves of Ligustrum obtusifolium Sieb.et Zucc.METHOD:Thin-layer scanning chromatography(TLC) was used.RESULTS The concentration of oleanolic acid was 0.395% in the fruit and 0.228% in the leaves.The average recovery rate was 99.3% and RSD was 2.08%.CONCLUSION The method is simple and reliable.The results are steady and reappearance is good.
2000, (3): 159-161.
Abstract:
OBJECTIVE To compare the feasbility of two methods in clinic.METHODS Rabbit plasma and sheep plasma were adopted to determine the potency of heparin sodium.RESULTS Sheep plasma method was easier than rabbit plasma.CONCLUSION We should adopt sheep plasma method to determine heprin sodium.
OBJECTIVE To compare the feasbility of two methods in clinic.METHODS Rabbit plasma and sheep plasma were adopted to determine the potency of heparin sodium.RESULTS Sheep plasma method was easier than rabbit plasma.CONCLUSION We should adopt sheep plasma method to determine heprin sodium.
Contribution System
Author Login
Review Login
Editor Login
Reader Login
News