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人类乙醛脱氢酶II及其激动剂的研究进展

田巍,  王涛,  郑灿辉,  董国强,  吕加国,  朱驹

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文章导航 > 药学实践与服务  > 2013 >  31(2): 94-97,112
田巍, 王涛, 郑灿辉, 董国强, 吕加国, 朱驹. 人类乙醛脱氢酶II及其激动剂的研究进展[J]. 药学实践与服务, 2013, 31(2): 94-97,112. doi: 10.3969/j.issn.1006-0111.2013.02.004
引用本文: 田巍, 王涛, 郑灿辉, 董国强, 吕加国, 朱驹. 人类乙醛脱氢酶II及其激动剂的研究进展[J]. 药学实践与服务, 2013, 31(2): 94-97,112. doi: 10.3969/j.issn.1006-0111.2013.02.004
shu
TIAN Wei, WANG Tao, ZHENG Can-hui, DONG Guo-qiang, LV jia-guo, ZHU Ju. Progress on Human aldehyde dehydrogenase II and its agonists[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 94-97,112. doi: 10.3969/j.issn.1006-0111.2013.02.004
Citation: TIAN Wei, WANG Tao, ZHENG Can-hui, DONG Guo-qiang, LV jia-guo, ZHU Ju. Progress on Human aldehyde dehydrogenase II and its agonists[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 94-97,112. doi: 10.3969/j.issn.1006-0111.2013.02.004
shu

人类乙醛脱氢酶II及其激动剂的研究进展

doi: 10.3969/j.issn.1006-0111.2013.02.004

  • 第二军医大学药学院药物化学教研室, 上海 200433

Progress on Human aldehyde dehydrogenase II and its agonists

  • Department of Medicinal Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • 摘要: 人类乙醛脱氢酶II (aldehyde dehydrogenasesII,ALDH2) 具有脱氢酶和酯酶等多种酶的功能,ALDH2活性的增强将减轻因酒精、缺血等多种因素引起的肝脏、心肌损伤及某些癌症的发生。本文通过对国内外文献的分析、整理和归纳,较为全面的介绍了ALDH2及其激动剂的研究现状。
    Abstract: The aldehyde dehydrogenase II (ALDH2) could act as both esterase and dehydrogenase. The improvement of ALDH2 activity might reduce the damage caused by alcohol and ischemia and avoid the occurrence of some certain cancers. The outline of ALDH2 and its agonists were summarized concisely through literature analysis, collation and induction in this paper.
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  • 收稿日期:  2012-04-26
  • 修回日期:  2012-11-12

人类乙醛脱氢酶II及其激动剂的研究进展

doi: 10.3969/j.issn.1006-0111.2013.02.004
  • 第二军医大学药学院药物化学教研室, 上海 200433
  • 收稿日期: 2012-04-26
  • 修回日期: 2012-11-12

摘要: 人类乙醛脱氢酶II (aldehyde dehydrogenasesII,ALDH2) 具有脱氢酶和酯酶等多种酶的功能,ALDH2活性的增强将减轻因酒精、缺血等多种因素引起的肝脏、心肌损伤及某些癌症的发生。本文通过对国内外文献的分析、整理和归纳,较为全面的介绍了ALDH2及其激动剂的研究现状。

English Abstract

田巍, 王涛, 郑灿辉, 董国强, 吕加国, 朱驹. 人类乙醛脱氢酶II及其激动剂的研究进展[J]. 药学实践与服务, 2013, 31(2): 94-97,112. doi: 10.3969/j.issn.1006-0111.2013.02.004
引用本文: 田巍, 王涛, 郑灿辉, 董国强, 吕加国, 朱驹. 人类乙醛脱氢酶II及其激动剂的研究进展[J]. 药学实践与服务, 2013, 31(2): 94-97,112. doi: 10.3969/j.issn.1006-0111.2013.02.004
shu
TIAN Wei, WANG Tao, ZHENG Can-hui, DONG Guo-qiang, LV jia-guo, ZHU Ju. Progress on Human aldehyde dehydrogenase II and its agonists[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 94-97,112. doi: 10.3969/j.issn.1006-0111.2013.02.004
Citation: TIAN Wei, WANG Tao, ZHENG Can-hui, DONG Guo-qiang, LV jia-guo, ZHU Ju. Progress on Human aldehyde dehydrogenase II and its agonists[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 94-97,112. doi: 10.3969/j.issn.1006-0111.2013.02.004
shu

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