利巴韦林和氟罗沙星葡萄糖注射液的配伍稳定性考察
Study on stability of compatibility of fleroxacin and glucose injection with ribavirin injection
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摘要: 目的: 考察氟罗沙星葡萄糖注射液和利巴韦林的配伍稳定性。 方法: 在25℃的避光和室内自然光条件下,用紫外分光光度法分别测定24 h内利巴韦林和氟罗沙星葡萄糖注射液配伍前后的含量变化情况,同时记录其外观及pH值变化。 结果: 利巴韦林和氟罗沙星平均回收率分别为99．52％,99．31％;RSD分别为0．450％,0．364％。常温放置6 h内配伍液外观、pH值、含量均无明显变化。 结论: 6 h内利巴韦林与氟罗沙星葡萄糖注射液配伍基本稳定。Abstract: Objective:To study the compatible stability of fleroxacin and glucose injection with ribavirin Injection. Methods: In the case of ambient temeratur(25℃),the changes in appearance and pH were observed,the content was determined by UV. Results: The average recoveries were 99.52% and 99.31%;RSD were 0.450% and 0.364%.The compatibility of fleroxaein and glucose injection with ribavirin injection had no significant changes in the aspect,pH,and content.Conclusin:The fleroxaein and glucose injection can be compatible with ribavirin injection,and be used within 6 h.
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Key words:
- fleroxacin /
- ribavirin /
- compatibility
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